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PTT is often falsely elevated in the situation of antiphospholipid antibody syndrome, during which the lupus anticoagulant antibody interferes with phospholipids used to induce in vitro coagulation. Having said that, the lupus anticoagulant antibody will cause a prothrombotic outcome in vivo, causing recurrent thromboses that characterize antiphospholipid antibody syndrome.

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Heparin is undoubtedly an anticoagulant that largely has an effect on the intrinsic pathway. PTT measurements enable make sure the patient is inside the therapeutic array, protecting against excessive bleeding and clot development.

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The scientific significance of prothrombin time lies in its utility for checking and controlling anticoagulant therapy, examining liver purpose, and diagnosing bleeding Issues.

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People that has a propensity for bleeding need to endure tests to find out the existence of a clotting disorder. For clients with deficiencies or defects from the intrinsic clotting cascade, the PTT will be elevated. Diseases using an elevated PTT include:

同时，特区检察院代表特区政府和四家博彩企业——永利渡假村、澳娱综合度假、美高梅金殿超濠与威尼斯人——对周焯华等人提出“连带责任”民事索赔。太阳城在这四家博彩企业的赌场内均有经营贵宾厅。

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The clinical significance of INR lies in its function in controlling and changing anticoagulant therapy to forestall equally too much bleeding and insufficient clotting.[seven]
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